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CD40 Ligation Induces Tissue Factor Expression in Human Vascular Smooth Muscle Cells

Tissue factor (TF) instigates the extrinsic pathway of blood coagulation. Plaque disruption and exposure of circulating factor VII/VIIa to subendothelial procoagulants such as TF leads to intravascular thrombosis, a frequent cause of acute atherosclerotic events. Although the expression of TF in the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schönbeck, Uwe, Mach, François, Sukhova, Galina K., Herman, Michael, Graber, Pierre, Kehry, Marilyn R., Libby, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868650/
https://ncbi.nlm.nih.gov/pubmed/10623647
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