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Down-Regulation of β(1C) Integrin in Breast Carcinomas Correlates with High Proliferative Fraction, High Histological Grade, and Larger Size

β(1C) integrin is an unspliced form of the integrin β(1) subfamily, which has been shown to inhibit cell proliferation in vitro. Using an affinity-purified rabbit antibody, we have investigated 283 previously untreated breast carcinomas, with the aim of ascertaining the actual prevalence of β(1C) ex...

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Detalhes bibliográficos
Main Authors: Manzotti, Michela, Dell’Orto, Patrizia, Maisonneuve, Patrick, Fornaro, Mara, Languino, Lucia R., Viale, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868633/
https://ncbi.nlm.nih.gov/pubmed/10623664
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