Detection of Epstein-Barr Virus in Hodgkin-Reed-Sternberg Cells : No Evidence for the Persistence of Integrated Viral Fragments in Latent Membrane Protein-1 (LMP-1)-Negative Classical Hodgkin’s Disease

Classical Hodgkin’s disease (HD) is associated with Epstein-Barr virus (EBV) infection. Although in developing countries EBV can be demonstrated in Hodgkin-Reed-Sternberg (H-RS) cells in up to 95% of HD cases, in industrialized countries only about 50% of HD cases are associated with EBV. An open qu...

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Bibliographic Details
Main Authors: Staratschek-Jox, Andrea, Kotkowski, Sascha, Belge, Gazanfer, Rüdiger, Thomas, Bullerdiek, Jörn, Diehl, Volker, Wolf, Jürgen
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868626/
https://ncbi.nlm.nih.gov/pubmed/10623669
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