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Conformational Proofreading: The Impact of Conformational Changes on the Specificity of Molecular Recognition

To perform recognition, molecules must locate and specifically bind their targets within a noisy biochemical environment with many look-alikes. Molecular recognition processes, especially the induced-fit mechanism, are known to involve conformational changes. This raises a basic question: Does molec...

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Detalhes bibliográficos
Main Authors: Savir, Yonatan, Tlusty, Tsvi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868595/
https://ncbi.nlm.nih.gov/pubmed/17520027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000468
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