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Distinct temporal programming of naive CD4(+) T cells for cell division versus TCR-dependent death susceptibility by antigen-presenting macrophages

Naive T cells become programmed for clonal expansion and contraction during the early hours of antigenic signaling. Recent studies support an ‘autopilot’ model, wherein the commitment to proliferate and the magnitude of the proliferative response are simultaneously determined during a single, brief...

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Detalhes bibliográficos
Main Authors: Schrum, Adam G., Palmer, Ed, Turka, Laurence A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868565/
https://ncbi.nlm.nih.gov/pubmed/15682456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200425635
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