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Mapping the interaction surface of linker histone H1° with the nucleosome of native chromatin in vivo
H1 linker histones stabilize the nucleosome, limit nucleosome mobility and facilitate the condensation of metazoan chromatin. Here, we have combined systematic mutagenesis, measurement of in vivo binding by photobleaching microscopy, and structural modeling to determine the binding geometry of the g...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2006
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1868459/ https://ncbi.nlm.nih.gov/pubmed/16462749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb1050 |
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