Lengsin is a survivor of an ancient family of class I glutamine synthetases in eukaryotes that has undergone evolutionary re-engineering for a role in the vertebrate eye lens.

Lengsin is a member of the glutamine synthetase (GS) superfamily expressed in the vertebrate eye lens. While the GS homology domains of lengsin are well conserved in all species examined, the N-terminal domain shows evidence of dynamic evolutionary changes. Compared with zebrafish and chicken, most...

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Hlavní autoři: Wyatt, Keith, White, Helen E., Wang, Luchun, Bateman, Orval A., Slingsby, Christine, Orlova, Elena V., Wistow, Graeme
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868402/
https://ncbi.nlm.nih.gov/pubmed/17161372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2006.10.008
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