Characterization of Dysplastic Aberrant Crypt Foci in the Rat Colon Induced by 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine

The multistage model of colon carcinogenesis is well established in both humans and experimental animals, and aberrant crypt foci (ACF) are generally assumed to be putative preneoplastic lesions of the colon. However, morphological analyses of ACF have suggested that they are highly heterogeneous in...

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Hauptverfasser: Ochiai, Masako, Ushigome, Mitsunori, Fujiwara, Kyoko, Ubagai, Tsuneyuki, Kawamori, Toshihiko, Sugimura, Takashi, Nagao, Minako, Nakagama, Hitoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2003
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868301/
https://ncbi.nlm.nih.gov/pubmed/14507667
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