Deficiency of NADPH Oxidase Components p47phox and gp91phox Caused Granulomatous Synovitis and Increased Connective Tissue Destruction in Experimental Arthritis Models

Recent studies indicated that the nicotinamide dinucleotide phosphate oxidase (NADPH) oxidase-derived oxygen radicals plays a deleterious role in arthritis. To study this in more detail, gonarthritis was induced in NADPH oxidase-deficient mice. Mice received an intraarticular injection of either zym...

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Bibliografische gegevens
Hoofdauteurs: van de Loo, Fons A. J., Bennink, Miranda B., Arntz, Onno J., Smeets, Ruben L., Lubberts, Erik, Joosten, Leo A. B., van Lent, Peter L. E. M., Coenen-de Roo, Christina J. J., Cuzzocrea, Salvatore, Segal, Brahm H., Holland, Steven M., van den Berg, Wim B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Investigative Pathology 2003
Onderwerpen:
Regular Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868292/
https://ncbi.nlm.nih.gov/pubmed/14507659
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