Complement C5 in Experimental Autoimmune Encephalomyelitis (EAE) Facilitates Remyelination and Prevents Gliosis

Activation of the classical complement system is known to play a central role in autoimmune demyelination. We have analyzed the role of complement component C5 in experimental autoimmune encephalomyelitis (EAE) using C5-deficient (C5-d) and C5-sufficient (C5-s) mice. Both groups of mice displayed ea...

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Bibliographic Details
Main Authors: Weerth, Susanna H., Rus, Horea, Shin, Moon L., Raine, Cedric S.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868269/
https://ncbi.nlm.nih.gov/pubmed/12937147
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