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Foreign Body-Type Multinucleated Giant Cell Formation Is Potently Induced by α-Tocopherol and Prevented by the Diacylglycerol Kinase Inhibitor R59022
Multinucleated foreign body giant cells (FBGCs) form by monocyte-derived macrophage fusion on implanted biomedical devices and are believed to mediate oxidative damage to biomaterial surfaces. Our in vitro system of human macrophage culture and interleukin (IL)-4-induced FBGC formation was developed...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Investigative Pathology
2003
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1868253/ https://ncbi.nlm.nih.gov/pubmed/12937156 |
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