Vascular Smooth Muscle Cells Orchestrate the Assembly of Type I Collagen via α2β1 Integrin, RhoA, and Fibronectin Polymerization

Assembly of collagen into fibrils is widely studied as a spontaneous and entropy-driven process. To determine whether vascular smooth muscle cells (SMCs) impact the formation of collagen fibrils, we microscopically tracked the conversion of soluble to insoluble collagen in human SMC cultures, using...

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Detalhes bibliográficos
Main Authors: Li, Shaohua, Van Den Diepstraten, Caroline, D’Souza, Sudhir J., Chan, Bosco M. C., Pickering, J. Geoffrey
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2003
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868248/
https://ncbi.nlm.nih.gov/pubmed/12937145
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