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Hypoxia-Inducible Erythropoietin Signaling in Squamous Dysplasia and Squamous Cell Carcinoma of the Uterine Cervix and Its Potential Role in Cervical Carcinogenesis and Tumor Progression

Tissue hypoxia is a characteristic property of cervical cancers that makes tumors resistant to chemo- and radiation therapy. Erythropoietin (Epo) is a hypoxia-inducible stimulator of erythropoiesis. Acting via its receptor (EpoR), Epo up-regulates bcl-2 and inhibits apoptosis of erythroid cells and...

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Bibliografski detalji
Glavni autori: Acs, Geza, Zhang, Paul J., McGrath, Cindy M., Acs, Peter, McBroom, John, Mohyeldin, Ahmed, Liu, Suzhen, Lu, Huasheng, Verma, Ajay
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2003
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868129/
https://ncbi.nlm.nih.gov/pubmed/12759237
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