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Evolutionary origins of insulin resistance: a behavioral switch hypothesis

BACKGROUND: Insulin resistance, which can lead to a number of diseases including type 2 diabetes and coronary heart disease, is believed to have evolved as an adaptation to periodic starvation. The "thrifty gene" and "thrifty phenotype" hypotheses constitute the dominant paradigm...

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Autori principali: Watve, Milind G, Yajnik, Chittaranjan S
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868084/
https://ncbi.nlm.nih.gov/pubmed/17437648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-7-61
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