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Evolutionary origins of insulin resistance: a behavioral switch hypothesis
BACKGROUND: Insulin resistance, which can lead to a number of diseases including type 2 diabetes and coronary heart disease, is believed to have evolved as an adaptation to periodic starvation. The "thrifty gene" and "thrifty phenotype" hypotheses constitute the dominant paradigm...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1868084/ https://ncbi.nlm.nih.gov/pubmed/17437648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-7-61 |
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