Fluorescence in Situ Hybridization Analysis of Immunoglobulin Heavy Chain Translocations in Plasma Cell Myeloma Using Intact Paraffin Sections and Simultaneous CD138 Immunofluorescence

Fluorescence in situ hybridization (FISH) studies are much more sensitive than classical cytogenetics for identification of karyotypic abnormalities in plasma cell myeloma. However, FISH analysis of bone marrow samples is often challenging because of a large number of admixed non-neoplastic hematopo...

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Detalhes bibliográficos
Main Authors: Cook, James R., Hartke, Marybeth, Pettay, James, Tubbs, Raymond R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867625/
https://ncbi.nlm.nih.gov/pubmed/16931586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2006.050149
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