Analysis of Molecular Alterations in Left- and Right-Sided Colorectal Carcinomas Reveals Distinct Pathways of Carcinogenesis : Proposal for New Molecular Profile of Colorectal Carcinomas

To clarify distinct genetic profiles of colorectal cancers based on tumor location (left- and right-sided), we evaluated the status of loss of heterozygosity (LOH), CpG islands methylation phenotype (CIMP), microsatellite instability (MSI), and mutations of p53, Ki-ras, and APC genes in 119 colorect...

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Detalhes bibliográficos
Main Authors: Sugai, Tamotsu, Habano, Wataru, Jiao, Yu-Fei, Tsukahara, Mitsunori, Takeda, Yuichiro, Otsuka, Koki, Nakamura, Shin-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867579/
https://ncbi.nlm.nih.gov/pubmed/16645205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2006.050052
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