Immunoglobulin Mutational Status Detected through Single-Round Amplification of Partial V(H) Region Represents a Good Prognostic Marker for Clinical Outcome in Chronic Lymphocytic Leukemia

The immunoglobulin (Ig) mutational status in B-cell chronic lymphocytic leukemia (CLL) distinguishes two subsets of patients with different prognosis. Ig status detection is commonly performed with a panel of V(H) family-specific primers. Although this method detects clonal VDJ rearrangement in virt...

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Detalhes bibliográficos
Main Authors: Marasca, Roberto, Maffei, Rossana, Morselli, Monica, Zucchini, Patrizia, Castelli, Ilaria, Martinelli, Silvia, Fontana, Marcella, Ravanetti, Sara, Curotti, Monica, Leonardi, Giovanna, Cagossi, Katia, Partesotti, Giovanni, Torelli, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2005
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867549/
https://ncbi.nlm.nih.gov/pubmed/16258154
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