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Evaluation of the Cepheid GeneXpert BCR-ABL Assay
Patients with chronic myeloid leukemia harbor the chromosomal translocation t(9;22), which corresponds to fusion of the BCR and ABL genes at the DNA level. The translated fusion product is an oncogenic protein with increased ABL tyrosine kinase activity causing cell transformation. To date, reverse...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1867453/ https://ncbi.nlm.nih.gov/pubmed/17384214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2007.060112 |
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