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Evaluation of the Cepheid GeneXpert BCR-ABL Assay
Patients with chronic myeloid leukemia harbor the chromosomal translocation t(9;22), which corresponds to fusion of the BCR and ABL genes at the DNA level. The translated fusion product is an oncogenic protein with increased ABL tyrosine kinase activity causing cell transformation. To date, reverse...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Investigative Pathology
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1867453/ https://ncbi.nlm.nih.gov/pubmed/17384214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2007.060112 |
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