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Evaluation of the Cepheid GeneXpert BCR-ABL Assay

Patients with chronic myeloid leukemia harbor the chromosomal translocation t(9;22), which corresponds to fusion of the BCR and ABL genes at the DNA level. The translated fusion product is an oncogenic protein with increased ABL tyrosine kinase activity causing cell transformation. To date, reverse...

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Bibliografische gegevens
Hoofdauteurs: Jobbagy, Zsolt, van Atta, Reuel, Murphy, Kathleen M., Eshleman, James R., Gocke, Christopher D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Investigative Pathology 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867453/
https://ncbi.nlm.nih.gov/pubmed/17384214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2007.060112
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