Loss of p63 Expression Is Associated with Tumor Progression in Bladder Cancer

p63, a member of the p53 gene family, encodes multiple proteins that may either transactivate p53 responsive genes (TAp63) or act as a dominant-negative factor toward p53 and p73 (ΔNp63). p63 is expressed in many epithelial compartments and p63(−/−) mice fail to develop skin, prostate, and mammary g...

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Autori principali: Urist, Marshall J., Di Como, Charles J., Lu, Ming-Lan, Charytonowicz, Elizabeth, Verbel, David, Crum, Christopher P., Ince, Tan A., McKeon, Frank D., Cordon-Cardo, Carlos
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867279/
https://ncbi.nlm.nih.gov/pubmed/12368193
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