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α-Methylacyl-CoA Racemase: Expression Levels of this Novel Cancer Biomarker Depend on Tumor Differentiation

α-Methylacyl-CoA racemase (AMACR) has previously been shown to be a highly sensitive marker for colorectal and clinically localized prostate cancer (PCa). However, AMACR expression was down-regulated at the transcript and protein level in hormone-refractory metastatic PCa, suggesting a hormone-depen...

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Autors principals: Kuefer, Rainer, Varambally, Sooryanarayana, Zhou, Ming, Lucas, Peter C., Loeffler, Martin, Wolter, Hubertus, Mattfeldt, Torsten, Hautmann, Richard E., Gschwend, Juergen E., Barrette, Terrence R., Dunn, Rodney L., Chinnaiyan, Arul M., Rubin, Mark A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867250/
https://ncbi.nlm.nih.gov/pubmed/12213712
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