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A Generalized Combinatorial Approach for Detecting Gene-by-Gene and Gene-by-Environment Interactions with Application to Nicotine Dependence

The determination of gene-by-gene and gene-by-environment interactions has long been one of the greatest challenges in genetics. The traditional methods are typically inadequate because of the problem referred to as the “curse of dimensionality.” Recent combinatorial approaches, such as the multifac...

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Main Authors: Lou, Xiang-Yang , Chen, Guo-Bo , Yan, Lei , Ma, Jennie Z. , Zhu, Jun , Elston, Robert C. , Li, Ming D. 
Formato: Artigo
Idioma:Inglês
Publicado: The American Society of Human Genetics 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867100/
https://ncbi.nlm.nih.gov/pubmed/17503330
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