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Loss of Cell Cycle Regulators p27(Kip1) and Cyclin E in Transitional Cell Carcinoma of the Bladder Correlates with Tumor Grade and Patient Survival

The cyclin-dependent kinase inhibitor p27(Kip1) is a powerful molecular determinant of cell cycle progression. Loss of expression of p27(Kip1) has been shown to be predictive of disease progression in several human malignancies. In this study we investigated the expression of two key cell cycle regu...

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Detalhes bibliográficos
Main Authors: Del Pizzo, Joseph J., Borkowski, Andrew, Jacobs, Stephen C., Kyprianou, Natasha
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867023/
https://ncbi.nlm.nih.gov/pubmed/10514396
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