Activation of NF-κB and c-jun Transcription Factors in Multiple Sclerosis Lesions : Implications for Oligodendrocyte Pathology

Oligodendrocytes are a major target of the purported autoimmune response in multiple sclerosis (MS) lesions, but little is known about the mechanisms underlying their demise. Despite the expression of proapoptotic receptors, these cells are rarely seen to undergo apoptosis in situ. On the other hand...

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Bibliographic Details
Main Authors: Bonetti, Bruno, Stegagno, Chiara, Cannella, Barbara, Rizzuto, Nicola, Moretto, Giuseppe, Raine, Cedric S.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 1999
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Short Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866971/
https://ncbi.nlm.nih.gov/pubmed/10550297
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