A High Frequency of Sequence Alterations Is Due to Formalin Fixation of Archival Specimens

Genomic analysis of archival tissues fixed in formalin is of fundamental importance in biomedical research, and numerous studies have used such material. Although the possibility of polymerase chain reaction (PCR)-introduced artifacts is known, the use of direct sequencing has been thought to overco...

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Detaylı Bibliyografya
Asıl Yazarlar: Williams, Cecilia, Pontén, Fredrik, Moberg, Catherine, Söderkvist, Peter, Uhlén, Mathias, Pontén, Jan, Sitbon, Gisela, Lundeberg, Joakim
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Investigative Pathology 1999
Konular:
Technical Advances
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866966/
https://ncbi.nlm.nih.gov/pubmed/10550302
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