Methylation Status of the Epstein-Barr Virus Major Latent Promoter C in Iatrogenic B Cell Lymphoproliferative Disease : Application of PCR-Based Analysis

The Epstein-Barr virus (EBV) major latent promoter C drives the expression of viral nuclear proteins important in lymphocyte immortalization and as targets for immune surveillance by cytotoxic T cells. Hypermethylation of the C promoter silences its transcription. This promoter is methylated and sil...

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Bibliographic Details
Main Authors: Tao, Qian, Swinnen, Lode J., Yang, Jie, Srivastava, Gopesh, Robertson, Keith D., Ambinder, Richard F.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866850/
https://ncbi.nlm.nih.gov/pubmed/10433954
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