Polarized Vascular Endothelial Growth Factor Secretion by Human Retinal Pigment Epithelium and Localization of Vascular Endothelial Growth Factor Receptors on the Inner Choriocapillaris : Evidence for a Trophic Paracrine Relation

The retinal pigment epithelium (RPE) maintains the choriocapillaris (CC) in the normal eye and is involved in the pathogenesis of choroidal neovascularization in age-related macular degeneration. Vascular endothelial growth factor-A (VEGF) is produced by differentiated human RPE cells in vitro and i...

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Main Authors: Blaauwgeers, Harriët G. T., Holtkamp, Gertjan M., Rutten, Hugo, Witmer, Antonella N., Koolwijk, Pieter, Partanen, Taina A., Alitalo, Kari, Kroon, Marielle E., Kijlstra, Aize, van Hinsbergh, Victor W. M., Schlingemann, Reinier O.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 1999
Fag:
Regular Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866848/
https://ncbi.nlm.nih.gov/pubmed/10433935
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