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Power and type I error rate of false discovery rate approaches in genome-wide association studies

In genome-wide genetic studies with a large number of markers, balancing the type I error rate and power is a challenging issue. Recently proposed false discovery rate (FDR) approaches are promising solutions to this problem. Using the 100 simulated datasets of a genome-wide marker map spaced about...

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Detalhes bibliográficos
Main Authors: Yang, Qiong, Cui, Jing, Chazaro, Irmarie, Cupples, L Adrienne, Demissie, Serkalem
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866802/
https://ncbi.nlm.nih.gov/pubmed/16451593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-6-S1-S134
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