Comparison of microsatellites, single-nucleotide polymorphisms (SNPs) and composite markers derived from SNPs in linkage analysis

There is growing evidence that a map of dense single-nucleotide polymorphisms (SNPs) can outperform a map of sparse microsatellites for linkage analysis. There is also argument as to whether a clustered SNP map can outperform an evenly spaced SNP map. Using Genetic Analysis Workshop 14 simulated dat...

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Bibliographische Detailangaben
Hauptverfasser: Xing, Chao, Schumacher, Fredrick R, Xing, Guan, Lu, Qing, Wang, Tao, Elston, Robert C
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2005
Schlagworte:
Proceedings
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866757/
https://ncbi.nlm.nih.gov/pubmed/16451638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-6-S1-S29
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