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Application of the propensity score in a covariate-based linkage analysis of the Collaborative Study on the Genetics of Alcoholism

BACKGROUND: Covariate-based linkage analyses using a conditional logistic model as implemented in LODPAL can increase the power to detect linkage by minimizing disease heterogeneity. However, each additional covariate analyzed will increase the degrees of freedom for the linkage test, and therefore...

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Autori principali: Doan, Betty Q, Frangakis, Constantine E, Shugart, Yin Y, Bailey-Wilson, Joan E
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866752/
https://ncbi.nlm.nih.gov/pubmed/16451643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-6-S1-S33
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