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Strategies for selecting subsets of single-nucleotide polymorphisms to genotype in association studies
In genetic association studies, linkage disequilibrium (LD) within a region can be exploited to select a subset of single-nucleotide polymorphisms (SNPs) to genotype with minimal loss of information. A novel entropy-based method for selecting SNPs is proposed and compared to an existing method based...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2005
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1866709/ https://ncbi.nlm.nih.gov/pubmed/16451686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-6-S1-S72 |
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