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Chimera Analysis Reveals That Fibroblasts and Endothelial Cells Require Platelet-Derived Growth Factor Receptorβ Expression for Participation in Reactive Connective Tissue Formation in Adults but Not during Development

The hypothesis that platelet-derived growth factor (PDGF) plays an important role in repair of connective tissue has been difficult to test experimentally, in part because the disruption of any of the PDGF ligand and receptor genes is embryonic lethal. We have developed a method that circumvents the...

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Detalhes bibliográficos
Main Authors: Crosby, Jeff R., Tappan, Kristen A., Seifert, Ronald A., Bowen-Pope, Daniel F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866587/
https://ncbi.nlm.nih.gov/pubmed/10329583
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