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Use of tree-based models to identify subgroups and increase power to detect linkage to cardiovascular disease traits

BACKGROUND: Our goal was to identify subgroups of sib pairs from the Framingham Heart Study data set that provided higher evidence of linkage to particular candidate regions for cardiovascular disease traits. The focus of this method is not to claim identification of significant linkage to a particu...

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Autori principali: Costello, Tracy Jennifer, Swartz, Michael David, Sabripour, Mahyar, Gu, Xiangjun, Sharma, Rishika, Etzel, Carol Jean
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866504/
https://ncbi.nlm.nih.gov/pubmed/14975134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-4-S1-S66
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