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Transmission ratio distortion in families from the Framingham Heart Study

BACKGROUND: One implicit assumption in most linkage analysis is that live-born siblings unselected for a phenotype do not share alleles greater than the Mendelian expectation at any particular locus. However, since most families are recruited for genetic studies because of the presence of disease, t...

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Detalhes bibliográficos
Main Authors: Paterson, Andrew D, Sun, Lei, Liu, Xiao-Qing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866484/
https://ncbi.nlm.nih.gov/pubmed/14975116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-4-S1-S48
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