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Pedigree and genotype errors in the Framingham Heart Study

The pedigree and genotype data from the Framingham Heart Study were examined for errors. Errors in 21 of 329 pedigrees were detected with the program PREST, and of these the errors in 16 pedigrees were resolved. Genotyping errors were then detected with SIMWALK2. Five Mendelian errors were found fol...

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Detalhes bibliográficos
Main Authors: Brush, Gerry, Almasy, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866477/
https://ncbi.nlm.nih.gov/pubmed/14975109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-4-S1-S41
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