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Linkage analysis of cross-sectional and longitudinally derived phenotypic measures to identify loci influencing blood pressure

BACKGROUND: The design of appropriate strategies to analyze and interpret linkage results for complex human diseases constitutes a challenge. Parameters such as power, definition of phenotype, and replicability have to be taken into account in order to reach meaningful conclusions. Incorporating dat...

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Detalhes bibliográficos
Main Authors: Shephard, Neil, Falcaro, Milena, Zeggini, Eleftheria, Chapman, Philip, Hinks, Anne, Barton, Anne, Worthington, Jane, Pickles, Andrew, John, Sally
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866461/
https://ncbi.nlm.nih.gov/pubmed/14975094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-4-S1-S26
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