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Power of maximum HLOD tests to detect linkage to obesity genes

BACKGROUND: We investigate the power of heterogeneity LOD test to detect linkage when a trait is determined by several major genes using Genetic Analysis Workshop 13 simulated data. We consider three traits, two of which are disease-causing traits: 1) the rate of change in body mass index (BMI); and...

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Detalhes bibliográficos
Main Authors: Yoo, Yun Joo, Huo, Yanling, Ning, Yuming, Gordon, Derek, Finch, Stephen, Mendell, Nancy R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866450/
https://ncbi.nlm.nih.gov/pubmed/14975084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-4-S1-S16
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