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HIV-1 Subtype B Protease and Reverse Transcriptase Amino Acid Covariation

Despite the high degree of HIV-1 protease and reverse transcriptase (RT) mutation in the setting of antiretroviral therapy, the spectrum of possible virus variants appears to be limited by patterns of amino acid covariation. We analyzed patterns of amino acid covariation in protease and RT sequences...

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Autors principals: Rhee, Soo-Yon, Liu, Tommy F, Holmes, Susan P, Shafer, Robert W
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866358/
https://ncbi.nlm.nih.gov/pubmed/17500586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0030087
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