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Loss of Heterozygosity and Microsatellite Instability in De Novo versus Ex-Adenoma Carcinomas of the Colorectum

Small adenocarcinomas of the colorectum showing no evidence of origin from an adenoma have been called de novo carcinomas, a name that implies an origin via a different molecular genetic mechanism than the usual colorectal carcinoma which develops from an adenoma. Using microsatellite analysis, 35 e...

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Detalhes bibliográficos
Main Authors: Mueller, James D., Haegle, Nina, Keller, Gisela, Mueller, Elke, Saretzky, Gabriele, Bethke, Birgit, Stolte, Manfred, Höfler, Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866329/
https://ncbi.nlm.nih.gov/pubmed/9846987
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