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Expression Status of p16 Protein Is Associated with Human Papillomavirus Oncogenic Potential in Cervical and Genital Lesions

The p16 protein (p16) is a cyclin-dependent kinase (CDK) inhibitor that decelerates the cell cycle by inactivating the CDKs that phosphorylate retinoblastoma (Rb) protein. Recent biological studies have revealed that p16 expression is markedly influenced by the status of Rb expression, and p16 overe...

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Detalhes bibliográficos
Main Authors: Sano, Takaaki, Oyama, Tetsunari, Kashiwabara, Kenji, Fukuda, Toshio, Nakajima, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866324/
https://ncbi.nlm.nih.gov/pubmed/9846965
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