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Purification method directly impacts effectiveness of an EGF-coupled targeting agent for noninvasive tumor detection in mice

Receptor targeting is an effective method of enhancing fluorescence signal in tumors for optical imaging. We previously used EGF conjugated to IRDye® 800CW to detect and track orthotopic prostate tumors in mice. In this study, our goal was to identify a reliable assay for targeting agent integrity i...

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Bibliografiske detaljer
Main Authors: Kovar, Joy L., Volcheck, William M., Chen, Jiyan, Simpson, Melanie A.
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866276/
https://ncbi.nlm.nih.gov/pubmed/17188228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2006.11.021
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