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Nucleation of protein fibrillation by nanoparticles

Nanoparticles present enormous surface areas and are found to enhance the rate of protein fibrillation by decreasing the lag time for nucleation. Protein fibrillation is involved in many human diseases, including Alzheimer's, Creutzfeld-Jacob disease, and dialysis-related amyloidosis. Fibril fo...

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Hlavní autoři: Linse, Sara, Cabaleiro-Lago, Celia, Xue, Wei-Feng, Lynch, Iseult, Lindman, Stina, Thulin, Eva, Radford, Sheena E., Dawson, Kenneth A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866183/
https://ncbi.nlm.nih.gov/pubmed/17485668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701250104
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