Impact of HIV on Cell Survival and Antiviral Activity of Plasmacytoid Dendritic Cells

Plasmacytoid dendritic cells (pDCs) are important mediators of innate immunity that act mainly through secretion of interferon (IFN)-α. Previous studies have found that these cells can suppress HIV in vitro; additionally, pDCs have been shown to be severely reduced in the peripheral blood of HIV-inf...

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Main Authors: Meyers, Jennifer Hartt, Justement, J. Shawn, Hallahan, Claire W., Blair, Eric T., Sun, Yongming A., O'Shea, M. Angeline, Roby, Gregg, Kottilil, Shyam, Moir, Susan, Kovacs, Colin M., Chun, Tae-Wook, Fauci, Anthony S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2007
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866176/
https://ncbi.nlm.nih.gov/pubmed/17520017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000458
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