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Degrons at the C Terminus of the Pathogenic but Not the Nonpathogenic Hantavirus G1 Tail Direct Proteasomal Degradation

Pathogenic hantaviruses cause two human diseases: hantavirus pulmonary syndrome (HPS) and hemorrhagic fever with renal syndrome (HFRS). The hantavirus G1 protein contains a long, 142-amino-acid cytoplasmic tail, which in NY-1 virus (NY-1V) is ubiquitinated and proteasomally degraded (E. Geimonen, I....

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Detalhes bibliográficos
Main Authors: Sen, Nandini, Sen, Adrish, Mackow, Erich R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866138/
https://ncbi.nlm.nih.gov/pubmed/17267477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02279-06
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