Characterization of Hepatitis B Virus (HBV)-Specific T-Cell Dysfunction in Chronic HBV Infection

Dysfunctional CD8(+) T cells present in chronic virus infections can express programmed death 1 (PD-1) molecules, and the inhibition of the engagement of PD-1 with its ligand (PD-L1) has been reported to enhance the antiviral function of these T cells. We took advantage of the wide fluctuations in l...

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Détails bibliographiques
Auteurs principaux: Boni, Carolina, Fisicaro, Paola, Valdatta, Caterina, Amadei, Barbara, Di Vincenzo, Paola, Giuberti, Tiziana, Laccabue, Diletta, Zerbini, Alessandro, Cavalli, Albertina, Missale, Gabriele, Bertoletti, Antonio, Ferrari, Carlo
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2007
Sujets:
Pathogenesis and Immunity
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866111/
https://ncbi.nlm.nih.gov/pubmed/17287266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02844-06
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