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Influenza A Virus NS1 Protein Activates the PI3K/Akt Pathway To Mediate Antiapoptotic Signaling Responses

Recently we have shown that influenza A virus infection leads to activation of the phosphatidylinositol 3-kinase (PI3K)/Akt pathway and that this cellular reaction is dependent on the expression of the viral nonstructural protein 1 (NS1). These data also suggested that PI3K activation confers a viru...

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Detalhes bibliográficos
Main Authors: Ehrhardt, Christina, Wolff, Thorsten, Pleschka, Stephan, Planz, Oliver, Beermann, Wiebke, Bode, Johannes G., Schmolke, Mirco, Ludwig, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866065/
https://ncbi.nlm.nih.gov/pubmed/17229704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02082-06
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