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Ability of Hyaluronidase 2 To Degrade Extracellular Hyaluronan Is Not Required for Its Function as a Receptor for Jaagsiekte Sheep Retrovirus

Jaagsiekte sheep retrovirus (JSRV) uses hyaluronidase 2 (Hyal2) as a cell entry receptor. By making inactivating mutations to the catalytic residues of human Hyal2, we found that hyaluronidase activity was dispensable for its receptor function. The affinities of the JSRV envelope glycoprotein for Hy...

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書誌詳細
主要な著者: Vigdorovich, Vladimir, Miller, A. Dusty, Strong, Roland K.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866058/
https://ncbi.nlm.nih.gov/pubmed/17229709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02177-06
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