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Murine Norovirus 1 Infection Is Associated with Histopathological Changes in Immunocompetent Hosts, but Clinical Disease Is Prevented by STAT1-Dependent Interferon Responses

Human noroviruses are the major cause of nonbacterial epidemic gastroenteritis worldwide. However, little is known regarding their pathogenesis or the immune responses that control them because until recently there has been no small animal model or cell culture system of norovirus infection. We rece...

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Detalhes bibliográficos
Main Authors: Mumphrey, Shannon M., Changotra, Harish, Moore, Tara N., Heimann-Nichols, Ellen R., Wobus, Christiane E., Reilly, Michael J., Moghadamfalahi, Mana, Shukla, Deepti, Karst, Stephanie M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866040/
https://ncbi.nlm.nih.gov/pubmed/17229692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02096-06
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