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Caspase 3-Dependent Cell Death of Neurons Contributes to the Pathogenesis of West Nile Virus Encephalitis

West Nile virus (WNV) is a neurotropic, arthropod-borne flavivirus that has become a significant global cause of viral encephalitis. To examine the mechanisms of WNV-induced neuronal death and the importance of apoptosis in pathogenesis, we evaluated the role of a key apoptotic regulator, caspase 3....

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Autori principali: Samuel, Melanie A., Morrey, John D., Diamond, Michael S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866006/
https://ncbi.nlm.nih.gov/pubmed/17192305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02311-06
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