Proteolytic Processing of the Ebola Virus Glycoprotein Is Not Critical for Ebola Virus Replication in Nonhuman Primates

Enveloped viruses often require cleavage of a surface glycoprotein by a cellular endoprotease such as furin for infectivity and virulence. Previously, we showed that Ebola virus glycoprotein does not require the furin cleavage motif for virus replication in cell culture. Here, we show that there are...

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Detaylı Bibliyografya
Asıl Yazarlar: Neumann, Gabriele, Geisbert, Thomas W., Ebihara, Hideki, Geisbert, Joan B., Daddario-DiCaprio, Kathleen M., Feldmann, Heinz, Kawaoka, Yoshihiro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2007
Konular:
Virus-Cell Interactions
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866002/
https://ncbi.nlm.nih.gov/pubmed/17229700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02486-06
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