Modulation of Gamma Interferon Receptor 1 by Mycobacterium tuberculosis: a Potential Immune Response Evasive Mechanism

Mycobacterium tuberculosis inhibits gamma interferon (IFN-γ)-mediated antimycobacterial action by adopting diverse mechanisms. IFN-γ binds to its receptor, IFN-γR, in order to initiate proper signaling. We have observed reduced surface expression levels of IFN-γ receptor 1 (IFN-γR1) in untreated pul...

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Hlavní autoři: Singhal, Amit, Jaiswal, Anand, Arora, Virendra K., Prasad, Hanumanthappa K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
Témata:
Host Response and Inflammation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865798/
https://ncbi.nlm.nih.gov/pubmed/17339358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01743-06
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